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Science 9 June 1978:
Vol. 200. no. 4346, pp. 1151 - 1153
DOI: 10.1126/science.200.4346.1151
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Articles

Visualization and Transport of Positron Emission from Proton Activation in vivo

G. W. BENNETT 1, J. O. ARCHAMBEAU 2, B. E. ARCHAMBEAU 3, J. I. MELTZER 4, and C. L. WINGATE 5

1 Department of Nuclear Energy, Brookhaven National Laboratory, Upton, New York 11973
2 Department of Radiation Oncology, City of Hope Medical Center, Duarte, California 91010
3 University of Chicago, Chicago, Illinois 60637
4 Department of Radiation Oncology, Nassau County Medical Center, East Meadow, New York 11554
5 Department of Radiology, School of Medicine, State University of New York, Stony Brook 11790

Heavy charged particle beams can be widely used for cancer therapy if control in heterogeneous tissue is proved practical. A beam of protons at 200 million electron volts has been visualized in plastic and in a living animal by using an on-line positron camera. The fraction of the activity retained in the radiation site was found to be at least 70 percent of that produced in a dead animal. The sensitivity of the technique was established for a typical geometry.

Submitted on December 5, 1977
Revised on February 28, 1978


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Tissue perfusion rate determined from the decay of oxygen-15 activity after photon activation in situ.
W. Hughes, G. Nussbaum, R Connolly, B Emami, and P Reilly (1979)
Science 204, 1215-1217
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