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ArticlesCopyright © 1978 by American Association for the Advancement of Science
Effect of oxygen pressure during culture on survival of mouse thyroid allografts
A marked increase in the percentage of mouse thyroids that retained function 20 days after transplantation across a major histocompatibility barrier and the percentage that lacked generalized infiltration was observed when the grafts received hyperbaric oxygen during a 4-day culture period. Perfusion of the donor animal before thyroidotomy and the addition of fetal calf serum to the culture medium did not have a significant effect on graft survival, but the percentage of grafts lacking generalized infiltration was slightly increased by the addition of hydrocortisone to the culture medium.
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Science. ISSN 0036-8075 (print), 1095-9203 (online)