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Science 28 April 1978:
Vol. 200. no. 4340, pp. 394 - 402
DOI: 10.1126/science.205944
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Articles

Science, Vol 200, Issue 4340, 394-402
Copyright © 1978 by American Association for the Advancement of Science

articles

Highly reiterated sequences of SIMIANSIMIANSIMIANSIMIANSIMIAN

H Rosenberg, M Singer, and M Rosenberg

A 172-base pair segment of DNA that is repeated several million times in the genome of the African green monkey has been characterized. Sequence analysis revealed that the many repeats of this complex unit are not all identical but represent a set of closely related segments: Sequence divergence occurs at various positions in the segment in a nonrandom manner. The uncloned segment obtained from monkey DNA is compared with a cloned segment of the same DNA which was recombined into the genome of simian virus 40 during permissive infection.


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