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Science 17 March 1978:
Vol. 199. no. 4334, pp. 1205 - 1206
DOI: 10.1126/science.305114
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Articles

Science, Vol 199, Issue 4334, 1205-1206
Copyright © 1978 by American Association for the Advancement of Science

articles

Irreversible inhibition of sodium entry sites in frog skin by a photosensitive amiloride analog

DJ Benos and LJ Mandel

A photosensitive binding reaction is described in which an analog of amiloride is bound to sites that control sodium entry into frog skin. This reaction results in irreversible inhibition of net sodium transport.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)