Science, Vol 199, Issue 4328, 544-545
Copyright © 1978 by American Association for the Advancement of Science
Cyclopropanecarboxylic acid: chain elongation to omega-cyclopropyl fatty acids by mammals and plants
DA Schooley,
GB Quistad,
and
LE Staiger
Rats dosed orally which [carboxyl-14C]cyclopropanecarboxylic acid (or its hexadecyl ester) retain radioactivity in tissue as novel triacylglycerols. The most abundant 14C-labeled metabolites were identified by gas-liquid chromatography-mass spectrometry as 13-cyclopropyltridecanoic and 15-cyclopropylpentadecanoic acids. Similar omega-cyclopropyl fatty acids are produced by beagle dogs and a lactating cow, as well as by apple and orange trees.