Science, Vol 199, Issue 4328, 538-539
Copyright © 1978 by American Association for the Advancement of Science
Double-stranded RNA is present in extracts of tobacco plants infected with tobacco mosaic virus
KS Derrick
Serologically specific electron microscopy was used to detect double-stranded RNA in extracts of tobacco infected with tobacco mosaic virus. Assays were made immediately after extraction, without purification, concentration, or treatment with phenol or detergent. This indicates that the double-stranded RNA is native and is not an artifact induced by purification methods.