Science, Vol 198, Issue 4319, 841-842
Copyright © 1977 by American Association for the Advancement of Science
Phototoxic keratoconjunctivitis from coal-tar pitch volatiles
EA Emmett,
L Stetzer,
and
B Taphorn
Roofers working with coal-tar pitch develop burning eyes and conjunctivitis which they subjectively associate with sun exposure. A coal-tar pitch distillate instilled in the conjunctivae of rabbits produced minimal or mild irritation in the absence of ultraviolet radiation, but irradiation with long-ultraviolet produced marked photophobia and severe keratoconjunctivitis.