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Science 16 September 1977:
Vol. 197. no. 4309, pp. 1187 - 1189
DOI: 10.1126/science.897661
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Articles

Science, Vol 197, Issue 4309, 1187-1189
Copyright © 1977 by American Association for the Advancement of Science

articles

Aluminum absorption and distribution: effect of parathyroid hormone

GH Mayor, JA Keiser, D Makdani, and PK Ku

In rats, gastrointestinal aluminum absorption and tissue distribution were altered by parathyroid hormone; the resultant tissue concentrations were similar to those observed in dialysis patients with a fatal encephalopathy. In dialysis patients, serum aluminum and endogenous parathyroid hormone concentrations are significantly correlated. These data suggest that aluminum toxicity in dialysis patients results from oral aluminum ingestion in the presence of hyperparathyroidism.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
The Effect of Oral Bases on Enteral Aluminum Absorption.
J. A. Walker, R. A. Sherman, and R. P. Cody (1990)
Arch Intern Med 150, 2037-2039
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Aluminum and Dialysis Dementia.
G. M. BERLYNE (1979)
Ann Intern Med 91, 496-498
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Dementia, Renal Failure, and Brain Aluminum.
A. I. ARIEFF, J. D. COOPER, D. ARMSTRONG, and V. C. LAZAROWITZ (1979)
Ann Intern Med 90, 741-747
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Dialysis Encephalopathy.
M. T. Schreeder (1979)
Arch Intern Med 139, 510-511
   Abstract »    PDF »
Progressive Dialysis Encephalopathy From Dialysate Aluminum.
V. V. Rozas, F. K. Port, and W. M. Rutt (1978)
Arch Intern Med 138, 1375-1377
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