Science, Vol 197, Issue 4301, 366-367
Copyright © 1977 by American Association for the Advancement of Science
Antibody-induced antigen redistribution and shedding from human breast cancer cells
RE Nordquist,
JH Anglin,
and
MP Lerner
Cell surface antigens of human breast cancer cells undergo a rapid redistribution when bound by antibodies from cancer patients. The subsequent shedding of these antigen-antibody complexes and free antigen may be instrumental in tumor survival.