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Science 8 July 1977:
Vol. 197. no. 4299, pp. 178 - 179
DOI: 10.1126/science.17916
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Articles

Science, Vol 197, Issue 4299, 178-179
Copyright © 1977 by American Association for the Advancement of Science

articles

Pineal vasotocin: release into cat cerebrospinal fluid by melanocyte-stimulating hormone release-inhibiting factor

S Pavel, R Goldstein, C Gheorghiu, and M Calb

The intracarotid injection of both synthetic melanocyte-stimulating hormone release-inhibiting factor (MIF) and purified MIF prepared from bovine hypothalami induces arginine vasotocin release into cerebrospinal fluid of cats and significantly decreases the pineal arginine vasotocin content at 5 minutes after the injection. The present results demonstrate an extrapituitary endocrine effect of synthetic and purified bovine MIF.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)