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Science 20 May 1977:
Vol. 196. no. 4292, pp. 899 - 900
DOI: 10.1126/science.323973
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Articles

Science, Vol 196, Issue 4292, 899-900
Copyright © 1977 by American Association for the Advancement of Science

articles

Prolactin-like immunoreactivity: localization in nerve terminals of rat hypothalamus

K Fuxe, T Hokfelt, P Eneroth, JA Gustafsson, and P Skett

Antibodies to rat prolactin were used in immunohistochemical studies of the hypothalamus and preoptic area of the rat. Evidence was obtained that a protein immunochemically related to prolactin was stored in networks of nerve terminals of many hypothalamic areas such as the arcuate nucleus, the dorsomedial hypothalamic nucleus, and periventricular regions of the hypothalamus and preoptic area. The neuronal storage of a prolactin-like protein in the hypothalamus was unaffected by hypophysectomy.


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