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Science 15 April 1977:
Vol. 196. no. 4287, pp. 307 - 308
DOI: 10.1126/science.557841
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Articles

Science, Vol 196, Issue 4287, 307-308
Copyright © 1977 by American Association for the Advancement of Science

articles

Stress-induced modulation of the immune response

AA Monjan and MI Collector

After mice were exposed to a daily auditory stressor for varying lengths of time, the responses of their splenic lymphoid cells in vitro were assessed. Both the blastogenic activity of concanavalin A or lipopolysaccharide and the ability of immune lymphocytes to lyse P815 target cells showed the same patterns of immunosuppression and enhancement.


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