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Science 4 March 1977:
Vol. 195. no. 4281, pp. 897 - 898
DOI: 10.1126/science.841316
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Articles

Science, Vol 195, Issue 4281, 897-898
Copyright © 1977 by American Association for the Advancement of Science

articles

Surface molecules of hematopoietic stem cells: requirement for sialic acid in spleen colony formation

Q Tonelli and RH Meintz

Enzymatic treatment was used to test the function of some surface peptides and carbohydrates in hematopoietic spleen colony formation. Proteases and most glycosidases had no effect on spleen colony formation, whereas treatment with Vibrio cholerae neuraminidase reduced colonies by one-half. Intact sialic acid (residues appear to play an important role in colony formation.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Homing of Human Cells in the Fetal Sheep Model: Modulation by Antibodies Activating or Inhibiting Very Late Activation Antigen-4-Dependent Function.
E. D. Zanjani, A. W. Flake, G. Almeida-Porada, N. Tran, and T. Papayannopoulou (1999)
Blood 94, 2515-2522
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