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Science 18 February 1977:
Vol. 195. no. 4279, pp. 687 - 688
DOI: 10.1126/science.841306
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Articles

Science, Vol 195, Issue 4279, 687-688
Copyright © 1977 by American Association for the Advancement of Science

articles

Does "blastocyst estrogen" initiate implantation?

Z Dickmann, JS Gupta, and SK Dey

Fertilized eggs were incubated for 2 hours in a medium containing estradiol-17beta and then transferred into the uteri of day 5 pseudopregnant rats. These eggs, but not estrogen-free control eggs, induced a local increase in capillary permeability. We suggest that the blastocyst factor which induces the local increase in capillary permeability during early pregnancy is estrogen synthesized by the blastocyst.


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S. R. Bair and S. H. Mellon (2004)
Mol. Cell. Biol. 24, 5383-5390
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Estrogen formation in the early rabbit embryo.
F. George and J. Wilson (1978)
Science 199, 200-201
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