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Science 11 February 1977:
Vol. 195. no. 4278, pp. 575 - 577
DOI: 10.1126/science.319531
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Articles

Science, Vol 195, Issue 4278, 575-577
Copyright © 1977 by American Association for the Advancement of Science

articles

Phenolic plant compounds functioning as reproductive inhibitors in Microtus montanus

PJ Berger, EH Sanders, PD Gardner, and NC Negus

Naturally occurring cinnamic acids and their related vinylphenols were found to inhibit reproductive function in Microtus montanus. When fed on these compounds, the rodents exhibited decreased uterine weight, inhibition of follicular development, and a cessation of breeding activity. It is suggested that these animals utilize plant compounds as a cue to terminate their reproductive effort in natural populations.


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4-Vinylphenol-Induced Pneumotoxicity and Hepatotoxicity in Mice.
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Precise Annual Changes in the Numbers of "Synaptic" Ribbons and Spherules in the Rat Pineal Gland.
M. Karasek, A. Lewinski, and L. Vollrath (1988)
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6-methoxybenzoxazolinone: a plant derivative that stimulates reproduction in Microtus montanus.
E. Sanders, P. Gardner, P. Berger, and N. Negus (1981)
Science 214, 67-69
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Experimental triggering of reproduction in a natural population of Microtus montanus.
N. Negus and P. Berger (1977)
Science 196, 1230-1231
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