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Science 4 February 1977:
Vol. 195. no. 4277, pp. 486 - 487
DOI: 10.1126/science.835005
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Articles

Science, Vol 195, Issue 4277, 486-487
Copyright © 1977 by American Association for the Advancement of Science

articles

Fluidity in the membranes of adult and neonatal human erythrocytes

M Kehry, J Yguerabide, and SJ Singer

Several antigens and receptors are mobile in the plane of the membrane of the intact neonatal human erythrocyte but not in the membrane of the normal adult cell. In this report, measurements of the fluorescence polarization of perylene dissolved in isolated erythrocyte membranes are reported, which are indistinguishable for the two kinds of cells. This result indicates that the viscosities of the membrane interiors of the two cells are the same. The observed mobility differences, therefore, cannot be attributed to different lipid viscosities in the two membranes.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)