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Science 21 January 1977:
Vol. 195. no. 4275, pp. 307 - 309
DOI: 10.1126/science.556653
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Articles

Science, Vol 195, Issue 4275, 307-309
Copyright © 1977 by American Association for the Advancement of Science

articles

Lateral transport of a lipid probe and labeled proteins on a cell membrane

J Schlessinger, D Axelrod, DE Koppel, WW Webb, and EL Elson

Diffusion coefficients (D) of a lipid probe and labeled proteins on L-6 myoblast membranes have been measured giving D(protein) approximately 2 X 10(-10) square centimeter per second and D (lipid probe) approximately 9 X 10(-9) square centimeter per second. Some of the membrane proteins are immobile, but the lipid probe diffuses freely over macroscopic distances. Cytochalasin B slows protein but not lipid probe diffusion.


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