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Science 3 December 1976:
Vol. 194. no. 4269, pp. 1057 - 1058
DOI: 10.1126/science.824734
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Articles

Science, Vol 194, Issue 4269, 1057-1058
Copyright © 1976 by American Association for the Advancement of Science

articles

Plasma alpha amino-n-butyric acid to leucine ratio: an empirical biochemical marker of alcoholism

S Shaw, B Stimmel, and CS Lieber

The plasma ratio of alpha-amino-n-butyric acid to leucine was elevated in ambulatory and hospitalized alcoholics as well as in baboons fed alcohol along with an adequate diet. There was a statistically significant positive correlation between this ratio and the degree of alcoholism assessed by three separate medical and psychological criteria in patients maintained on methadone.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Standard or Branched-Chain Amino Acid Infusions as Short-Term Nutritional Support in Liver Cirrhosis?.
E. Rocchi, M. Cassanelli, P. Gibertini, A. Pietrangelo, G. Casalgrandi, and E. Ventura (1985)
JPEN J Parenter Enteral Nutr 9, 447-451
   Abstract »    PDF »
Ratio of plasma alpha amino-n-butyric acid to leucine as an empirical marker of alcoholism: diagnostic value.
M. Morgan, J. Milsom, and S Sherlock (1977)
Science 197, 1183-1185
   Abstract »    PDF »


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