Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 3 December 1976:
Vol. 194. no. 4269, pp. 1055 - 1057
DOI: 10.1126/science.982059
Prev | Table of Contents | Next

Articles

Science, Vol 194, Issue 4269, 1055-1057
Copyright © 1976 by American Association for the Advancement of Science

articles

Effect of charcoal-broiled beef on phenacetin metabolism in man

EJ Pantuck, KC Hsiao, AH Conney, WA Garland, A Kappas, KE Anderson, and AP Alvares

When charcoal-broiled beef was fed to human volunteers, who were then given phenacetin orally, the concentration of phenacetin in the plasma was lowered, but its half-life in the plasma was not changed. The data suggest that feeding charcoal-broiled beef enhances the metabolism of orally administered phenacetin in the intestine or during its first pass through the liver, or both.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Ah locus: genetic differences in susceptibility to cataracts induced by acetaminophen.
H Shichi, D. Gaasterland, N. Jensen, and D. Nebert (1978)
Science 200, 539-541
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)