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Science 26 November 1976:
Vol. 194. no. 4268, pp. 946 - 948
DOI: 10.1126/science.10628
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Articles

Science, Vol 194, Issue 4268, 946-948
Copyright © 1976 by American Association for the Advancement of Science

articles

Ovum aging and pH imbalance as a cause of chromosomal anomalies in the hamster

K Adachi and TH Ingalls

Using female hamsters mated in estrus, we have produced triploid embryos as manifestations of pregnancy wastage by combining delays of 3 to 4 hours in ferilization with exposure of the animals to hypoxia. Among the triploid embryos only XXX and XXY karotypes occurred, indicating derivation from XX-containing ova. These findings have relevance to human reproduction.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)