Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 22 October 1976:
Vol. 194. no. 4263, pp. 426 - 428
DOI: 10.1126/science.982024
Prev | Table of Contents | Next

Articles

Science, Vol 194, Issue 4263, 426-428
Copyright © 1976 by American Association for the Advancement of Science

articles

Reinnervation of dentate gyrus by homologous afferents following entorhinal cortical lesions in adult rats

O Steward

Granule cells of the rat dentate gyrus which are denervated by unilateral destruction of the entorhinal cortex are reinnervated in part by proliferation of surviving pathways from the contralateral entorhinal cortex. The cells of origin of these lesion-induced projections were identified by retrograde labeling with horseradish peroxidase and were the same cell type which normally project to the ipsilateral dentate gyrus


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Expression of a Familial Alzheimer's Disease-Linked Presenilin-1 Variant Enhances Perforant Pathway Lesion-Induced Neuronal Loss in the Entorhinal Cortex.
O. Lazarov, L. D. Peterson, D. A. Peterson, and S. S. Sisodia (2006)
J. Neurosci. 26, 429-434
   Abstract »    Full Text »    PDF »
Matrix Metalloproteinase Inhibition Alters Functional and Structural Correlates of Deafferentation-Induced Sprouting in the Dentate Gyrus.
T. M. Reeves, M. L. Prins, J. Zhu, J. T. Povlishock, and L. L. Phillips (2003)
J. Neurosci. 23, 10182-10189
   Abstract »    Full Text »    PDF »
Evidence That Synaptically Released beta -Amyloid Accumulates as Extracellular Deposits in the Hippocampus of Transgenic Mice.
O. Lazarov, M. Lee, D. A. Peterson, and S. S. Sisodia (2002)
J. Neurosci. 22, 9785-9793
   Abstract »    Full Text »    PDF »
The Critical Role of Basement Membrane-Independent Laminin gamma 1 Chain during Axon Regeneration in the CNS.
B. Grimpe, S. Dong, C. Doller, K. Temple, A. T. Malouf, and J. Silver (2002)
J. Neurosci. 22, 3144-3160
   Abstract »    Full Text »    PDF »
Molecular and functional analysis of hyperpolarization-activated pacemaker channels in the hippocampus after entorhinal cortex lesion.
A. U. BRAUER, N. E. SAVASKAN, M. H. P. KOLE, M. PLASCHKE, L. M. MONTEGGIA, E. J. NESTLER, E. SIMBURGER, R. A. DEISZ, O. NINNEMANN, and R. NITSCH (2001)
FASEB J 15, 2689-2701
   Abstract »    Full Text »    PDF »
Spontaneous corticospinal axonal plasticity and functional recovery after adult central nervous system injury.
N. Weidner, A. Ner, N. Salimi, and M. H. Tuszynski (2001)
PNAS 98, 3513-3518
   Abstract »    Full Text »    PDF »
Heat transfer from starlings sturnus vulgaris during flight.
S Ward, J. Rayner, U MOLler, D. Jackson, W Nachtigall, and J. Speakman (1999)
J. Exp. Biol. 202, 1589-1602
   Abstract »
Endogenous FGF-2 Is Important for Cholinergic Sprouting in the Denervated Hippocampus.
A. M. Fagan, S. T. Suhr, C. A. Lucidi-Phillipi, D. A. Peterson, D. M. Holtzman, and F. H. Gage (1997)
J. Neurosci. 17, 2499-2511
   Abstract »    Full Text »    PDF »
Progressive entorhinal cortex lesions accelerate hippocampal sprouting and spare spatial memory in rats.
J. J. Ramirez, M. McQuilkin, T. Carrigan, K. MacDonald, and M. S. Kelley (1996)
PNAS 93, 15512-15517
   Abstract »    Full Text »    PDF »
Progressive Unilateral Damage of the Entorhinal Cortex Enhances Synaptic Efficacy of the Crossed Entorhinal Afferent to Dentate Granule Cells.
J. J. Ramirez, K. Bulsara, S. C. Moore, K. Ruch, and W. Abrams (1999)
J. Neurosci. 19, RC42
   Abstract »    Full Text »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)