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Science 10 September 1976:
Vol. 193. no. 4257, pp. 1011 - 1013
DOI: 10.1126/science.948757
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Articles

Science, Vol 193, Issue 4257, 1011-1013
Copyright © 1976 by American Association for the Advancement of Science

articles

Modulation of C3b hemolytic activity by a plasma protein distinct from C3b inactivator

K Whaley and S Ruddy

A human plasma protein binds to cell-bound C3b, the major cleavage product of the third component of complement. Consequent upon this binding, C3b no longer functions in either the classical or alternative pathways. This C3b inhibitory activity is a property of a protein previously designated beta 1H on the basis of its electrophoretic mobility.


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