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Science 20 August 1976:
Vol. 193. no. 4254, pp. 683 - 685
DOI: 10.1126/science.181842
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Articles

Science, Vol 193, Issue 4254, 683-685
Copyright © 1976 by American Association for the Advancement of Science

articles

Dopamine-sensitive adenylate cyclase occurs in a region of substantia nigra containing dopaminergic dendrites

JW Kebabian and JM Saavedra

The zona reticulata, the subdivision of the substantia nigra containing dendrites of the dopaminergic nigro-neostriatal neurons, contains dopamine-sensitive adenylate cyclase activity. This nigral dopamine receptor is similar to the striatal dopamine receptor. These and previous data suggest a physiological role (or roles) for dopamine in the substantia nigra.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Advances in the Neuropharmacology of Parkinsonism.
D. B. CALNE, J. KEBABIAN, E. SILBERGELD, and E. EVARTS (1979)
Ann Intern Med 90, 219-229
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Interdependence of the nigrostriatal dopaminergic systems on the two sides of the brain in the cat.
A Nieoullon, A Cheramy, and J Glowinski (1977)
Science 198, 416-418
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An adenylate cyclase of brain reflects propensity for breast cancer in mice.
G. Cotzias and L. Tang (1977)
Science 197, 1094-1096
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Localization of nigral dopamine-sensitive adenylate cyclase on neurons originating from the corpus striatum.
P. Spano, M Trabucchi, and G Di Chiara (1977)
Science 196, 1343-1345
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Dopamine-sensitive adenylate cyclase: location in substantia nigra.
K Gale, A Guidotti, and E Costa (1977)
Science 195, 503-505
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