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Science 23 July 1976:
Vol. 193. no. 4250, pp. 328 - 332
DOI: 10.1126/science.180602
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Articles

Science, Vol 193, Issue 4250, 328-332
Copyright © 1976 by American Association for the Advancement of Science

articles

Embryonal neoplasms in the opossum: a new model for solid tumors of infancy and childhood

W Jurgelski Jr, PM Hudson, HL Falk, and P Kotin

Opossums fed the chemical carcinogen ethyl nitrosourea early in postnatal life developed a variety of epithelial and mesenchymal embryonal neoplasms that were closely analogous, in morphology and biological behavior, to tumors of human infancy and childhood for which experimental models in laboratory animals are either imprecise or nonexistent. The embryonal tumors were found in association with, and occasionally at the same sites as, a limited number of malformations.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
The Marsupial as a Biomedical Model.
W. Jurgelski (1984)
International Journal of Toxicology 3, 343-355
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Science. ISSN 0036-8075 (print), 1095-9203 (online)