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Science 28 May 1976:
Vol. 192. no. 4242, pp. 907 - 908
DOI: 10.1126/science.1273576
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Articles

Science, Vol 192, Issue 4242, 907-908
Copyright © 1976 by American Association for the Advancement of Science

articles

Vasoactive intestinal polypeptide: abundant immunoreactivity in neural cell lines and normal nervous tissue

SI Said and RN Rosenberg

Vasoactive intestinal polypeptide immunoreactivity is present in high concentrations in clonal lines of neuronal and glial origin. The central nervous system and sympathetic ganglia are also rich in the peptide. The findings suggest that this peptide, hitherto thought limited to the gastrointestinal tract, is widely distributed in neural tissue and may have broad physiological significance.


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