Science 21 May 1976: Vol. 192. no. 4241, pp. 799 - 801 DOI: 10.1126/science.1265483

Prev | Table of Contents | Next

Articles

Photoreceptors Repair by Autologous Transplantation of Retinal Pigment Epithelium and Partial-Thickness Choroid Graft in Rabbits.

T. Zhang, Y. Hu, Y. Li, J. Wu, L. Zhao, C. Wang, Y. Liu, Z. Yin, and Z. Ma (2009)
Invest. Ophthalmol. Vis. Sci. 50, 2982-2988
 |  Abstract »  |  Full Text »  |  PDF »

The Age Lipid A2E and Mitochondrial Dysfunction Synergistically Impair Phagocytosis by Retinal Pigment Epithelial Cells.

C. Vives-Bauza, M. Anand, A. K. Shirazi, J. Magrane, J. Gao, H. R. Vollmer-Snarr, G. Manfredi, and S. C. Finnemann (2008)
J. Biol. Chem. 283, 24770-24780
 |  Abstract »  |  Full Text »  |  PDF »

Restoration of Visual Response in Aged Dystrophic RCS Rats Using AAV-Mediated Channelopsin-2 Gene Transfer.

H. Tomita, E. Sugano, H. Yawo, T. Ishizuka, H. Isago, S. Narikawa, S. Kugler, and M. Tamai (2007)
Invest. Ophthalmol. Vis. Sci. 48, 3821-3826
 |  Abstract »  |  Full Text »  |  PDF »

The Requirement of Pax6 for Postnatal Eye Development: Evidence from Experimental Mouse Chimeras.

S. Li, D. Goldowitz, and D. J. Swanson (2007)
Invest. Ophthalmol. Vis. Sci. 48, 3292-3300
 |  Abstract »  |  Full Text »  |  PDF »

Noncell-autonomous photoreceptor degeneration in a zebrafish model of choroideremia.

B. L. Krock, J. Bilotta, and B. D. Perkins (2007)
PNAS 104, 4600-4605
 |  Abstract »  |  Full Text »  |  PDF »

Visual response properties of retinal ganglion cells in the royal college of surgeons dystrophic rat..

M. Pu, L. Xu, and H. Zhang (2006)
Invest. Ophthalmol. Vis. Sci. 47, 3579-3585
 |  Abstract »  |  Full Text »  |  PDF »

In Vivo Imaging of the Photoreceptor Mosaic in Retinal Dystrophies and Correlations with Visual Function.

S. S. Choi, N. Doble, J. L. Hardy, S. M. Jones, J. L. Keltner, S. S. Olivier, and J. S. Werner (2006)
Invest. Ophthalmol. Vis. Sci. 47, 2080-2092
 |  Abstract »  |  Full Text »  |  PDF »

Light-induced Oxidation of Photoreceptor Outer Segment Phospholipids Generates Ligands for CD36-mediated Phagocytosis by Retinal Pigment Epithelium: A POTENTIAL MECHANISM FOR MODULATING OUTER SEGMENT PHAGOCYTOSIS UNDER OXIDANT STRESS CONDITIONS.

M. Sun, S. C. Finnemann, M. Febbraio, L. Shan, S. P. Annangudi, E. A. Podrez, G. Hoppe, R. Darrow, D. T. Organisciak, R. G. Salomon, et al. (2006)
J. Biol. Chem. 281, 4222-4230
 |  Abstract »  |  Full Text »  |  PDF »

MOSAICISM OF THE RETINAL PIGMENT EPITHELIUM: seeing the small picture.

J. M. Burke and L. M. Hjelmeland (2005)
Mol. Interv. 5, 241-249
 |  Abstract »  |  Full Text »  |  PDF »

The Retinal Pigment Epithelium in Visual Function.

O. Strauss (2005)
Physiol Rev 85, 845-881
 |  Abstract »  |  Full Text »  |  PDF »

Neuroprotective Effect of Subretinal Implants in the RCS Rat.

M. T. Pardue, M. J. Phillips, H. Yin, B. D. Sippy, S. Webb-Wood, A. Y. Chow, and S. L. Ball (2005)
Invest. Ophthalmol. Vis. Sci. 46, 674-682
 |  Abstract »  |  Full Text »  |  PDF »

Loss of Synchronized Retinal Phagocytosis and Age-related Blindness in Mice Lacking {alpha}v{beta}5 Integrin.

E. F. Nandrot, Y. Kim, S. E. Brodie, X. Huang, D. Sheppard, and S. C. Finnemann (2004)
J. Exp. Med. 200, 1539-1545
 |  Abstract »  |  Full Text »  |  PDF »

Changes in Retinal Pigment Epithelial Gene Expression Induced by Rod Outer Segment Uptake.

I. Chowers, Y. Kim, R. H. Farkas, T. L. Gunatilaka, A. S. Hackam, P. A. Campochiaro, S. C. Finnemann, and D. J. Zack (2004)
Invest. Ophthalmol. Vis. Sci. 45, 2098-2106
 |  Abstract »  |  Full Text »  |  PDF »

Prosaposin Gene Expression in Normal and Dystrophic RCS Rat Retina.

L. Van Den Berghe, K. Sainton, K. Gogat, D. Marchant, E. Dufour, S. Bonnel, S. Gadin, M. Menasche, and M. Abitbol (2004)
Invest. Ophthalmol. Vis. Sci. 45, 1297-1305
 |  Abstract »  |  Full Text »  |  PDF »

MERTK Arginine-844-Cysteine in a Patient with Severe Rod-Cone Dystrophy: Loss of Mutant Protein Function in Transfected Cells.

C. L. McHenry, Y. Liu, W. Feng, A. R. Nair, K. L. Feathers, X. Ding, A. Gal, D. Vollrath, P. A. Sieving, and D. A. Thompson (2004)
Invest. Ophthalmol. Vis. Sci. 45, 1456-1463
 |  Abstract »  |  Full Text »  |  PDF »

Analysis of the VMD2 Promoter and Implication of E-box Binding Factors in Its Regulation.

N. Esumi, Y. Oshima, Y. Li, P. A. Campochiaro, and D. J. Zack (2004)
J. Biol. Chem. 279, 19064-19073
 |  Abstract »  |  Full Text »  |  PDF »

Quantification of Spatial Vision in the Royal College of Surgeons Rat.

T. J. McGill, R. M. Douglas, R. D. Lund, and G. T. Prusky (2004)
Invest. Ophthalmol. Vis. Sci. 45, 932-936
 |  Abstract »  |  Full Text »  |  PDF »

Accumulation of Neurocan, a Brain Chondroitin Sulfate Proteoglycan, in Association with the Retinal Vasculature in RCS Rats.

Y. Zhang, U. Rauch, and M.-T. R. Perez (2003)
Invest. Ophthalmol. Vis. Sci. 44, 1252-1261
 |  Abstract »  |  Full Text »  |  PDF »

An RCS-Like Retinal Dystrophy Phenotype in Mer Knockout Mice.

J. L. Duncan, M. M. LaVail, D. Yasumura, M. T. Matthes, H. Yang, N. Trautmann, A. V. Chappelow, W. Feng, H. S. Earp, G. K. Matsushima, et al. (2003)
Invest. Ophthalmol. Vis. Sci. 44, 826-838
 |  Abstract »  |  Full Text »  |  PDF »

Limitation of Anatomical Integration between Subretinal Transplants and the Host Retina.

Y. Zhang, K. Arner, B. Ehinger, and M.-T. R. Perez (2003)
Invest. Ophthalmol. Vis. Sci. 44, 324-331
 |  Abstract »  |  Full Text »  |  PDF »

Retinal pigment epithelial cells phagocytosis of T lymphocytes: possible implication in the immune privilege of the eye.

F Willermain, L Caspers-Velu, B Nowak, P Stordeur, R Mosselmans, I Salmon, T Velu, and C Bruyns (2002)
Br J Ophthalmol 86, 1417-1421
 |  Abstract »  |  Full Text »  |  PDF »

Mertk Triggers Uptake of Photoreceptor Outer Segments during Phagocytosis by Cultured Retinal Pigment Epithelial Cells.

W. Feng, D. Yasumura, M. T. Matthes, M. M. LaVail, and D. Vollrath (2002)
J. Biol. Chem. 277, 17016-17022
 |  Abstract »  |  Full Text »  |  PDF »

Effect of Rpe65 Knockout on Accumulation of Lipofuscin Fluorophores in the Retinal Pigment Epithelium.

M. L. Katz and T. M. Redmond (2001)
Invest. Ophthalmol. Vis. Sci. 42, 3023-3030
 |  Abstract »  |  Full Text »  |  PDF »

A Mutation of Early Photoreceptor Development, mikre oko, Reveals Cell-Cell Interactions Involved in the Survival and Differentiation of Zebrafish Photoreceptors.

G. Doerre and J. Malicki (2001)
J. Neurosci. 21, 6745-6757
 |  Abstract »  |  Full Text »  |  PDF »

Fibroblast Growth Factor-2 Decreases Hyperoxia-Induced Photoreceptor Cell Death in Mice.

H. Yamada, E. Yamada, A. Ando, N. Esumi, N. Bora, J. Saikia, C.-H. Sung, D. J. Zack, and P. A. Campochiaro (2001)
Am. J. Pathol. 159, 1113-1120
 |  Abstract »  |  Full Text »  |  PDF »

Retinal Transplants Restore Visually Evoked Responses in Rats with Photoreceptor Degeneration.

G. Woch, R. B. Aramant, M. J. Seiler, B. T. Sagdullaev, and M. A. McCall (2001)
Invest. Ophthalmol. Vis. Sci. 42, 1669-1676
 |  Abstract »  |  Full Text »

Extended Photoreceptor Viability by Light Stress in the RCS Rats but not in the Opsin P23H Mutant Rats.

I. Nir, J. M. Harrison, C. Liu, and R. Wen (2001)
Invest. Ophthalmol. Vis. Sci. 42, 842-849
 |  Abstract »  |  Full Text »

Ambient Hypoxia Reverses Retinal Vascular Attenuation in a Transgenic Mouse Model of Autosomal Dominant Retinitis Pigmentosa.

J. S. Penn, S. Li, and M. I. Naash (2000)
Invest. Ophthalmol. Vis. Sci. 41, 4007-4013
 |  Abstract »  |  Full Text »

Molecular ophthalmology: an update on animal models for retinal degenerations and dystrophies.

F HAFEZI, C GRIMM, B C SIMMEN, A WENZEL, and C E REMÉ (2000)
Br J Ophthalmol 84, 922-927
 |  Full Text »

Mutation of the receptor tyrosine kinase gene Mertk in the retinal dystrophic RCS rat.

P. M. D'Cruz, D. Yasumura, J. Weir, M. T. Matthes, H. Abderrahim, M. M. LaVail, and D. Vollrath (2000)
Hum. Mol. Genet. 9, 645-651
 |  Abstract »  |  Full Text »  |  PDF »

Progressive Optic Axon Dystrophy and Vascular Changes in rd Mice.

S. Wang, M. P. Villegas–Pérez, M. Vidal–Sanz, and R. D. Lund (2000)
Invest. Ophthalmol. Vis. Sci. 41, 537-545
 |  Abstract »  |  Full Text »

The Implications of Rod-Dependent Cone Survival for Basic and Clinical Research.

D. Hicks and J. Sahel (1999)
Invest. Ophthalmol. Vis. Sci. 40, 3071-3074
 |  Full Text »  |  PDF »

Low Expression of {alpha}A-Crystallins and Rhodopsin Kinase of Photoreceptors in Retinal Dystrophy Rat.

A. Maeda, H. Ohguro, T. Maeda, T. Nakagawa, and Y. Kuroki (1999)
Invest. Ophthalmol. Vis. Sci. 40, 2788-2794
 |  Abstract »  |  Full Text »  |  PDF »

Light Treatment Enhances Photoreceptor Survival in Dystrophic Retinas of Royal College of Surgeons Rats.

I. Nir, C. Liu, and R. Wen (1999)
Invest. Ophthalmol. Vis. Sci. 40, 2383-2390
 |  Abstract »  |  Full Text »  |  PDF »

Caspaselike Proteases Activated in Apoptotic Photoreceptors of Royal College of Surgeons Rats.

N. Katai, T. Kikuchi, H. Shibuki, S. Kuroiwa, J. Arai, T. Kurokawa, and N. Yoshimura (1999)
Invest. Ophthalmol. Vis. Sci. 40, 1802-1886
 |  Abstract »  |  Full Text »  |  PDF »

Management of inherited outer retinal dystrophies: present and future.

N H V. CHONG and A. C BIRD (1999)
Br J Ophthalmol 83, 120-122
 |  Full Text »

A unique pattern of photoreceptor degeneration in cyclin D1 mutant mice.

C. Ma, D. Papermaster, and C. L. Cepko (1998)
PNAS 95, 9938-9943
 |  Abstract »  |  Full Text »  |  PDF »

Normal retina releases a diffusible factor stimulating cone survival in the retinal degeneration mouse.

S. Mohand-Said, A. Deudon-Combe, D. Hicks, M. Simonutti, V. Forster, A.-C. Fintz, T. Leveillard, H. Dreyfus, and J.-A. Sahel (1998)
PNAS 95, 8357-8362
 |  Abstract »  |  Full Text »  |  PDF »

Phagocytosis of rod outer segments by retinal pigment epithelial cells requires alpha vbeta 5 integrin for binding but not for internalization.

S. C. Finnemann, V. L. Bonilha, A. D. Marmorstein, and E. Rodriguez-Boulan (1997)
PNAS 94, 12932-12937
 |  Abstract »  |  Full Text »  |  PDF »

Gene therapy for inherited retinal degeneration.

R R ALI, M B REICHEL, D M HUNT, and S S BHATTACHARYA (1997)
Br J Ophthalmol 81, 795-801
 |  Full Text »  |  PDF »

Vertebrate Unconventional Myosins.

T. Hasson and M. S. Mooseker (1996)
J. Biol. Chem. 271, 16431-16434
 |  Full Text »  |  PDF »

Repair and Replacement to Restore Sight: Report From the Panel on Photoreceptor/Retinal Pigment Epithelium.

D. Bok, G. S. Hageman, R. H. Steinberg, and Photoreceptor/Retinal Pigment Epithelium Panel (1993)
Arch Ophthalmol 111, 463-471
 |  Abstract »  |  PDF »

Transplantation of Retinal Pigment Epithelial Cells: Scientific Advance and Social Responsibility.

G. A. Fishman (1988)
Arch Ophthalmol 106, 1667-1668
 |  Abstract »  |  PDF »

Retinal dystrophy: development retarded by galactose feeding in spontaneously hypertensive rats.

R. Frank, R. Keirn, G. Keirn, M. Mancini, and J. Khoury (1986)
Science 231, 376-378
 |  Abstract »  |  PDF »

Histological demonstration of mosaicism in a series of chimeric rats produced between congenic strains.

W. Weinberg, J. Howard, and P. Iannaccone (1985)
Science 227, 524-527
 |  Abstract »  |  PDF »

Heredofamilial Retinal Dystrophy in Guinea Baboons: I. A Histopathologic Study.

M. O. M. Tso, R. M. Santos-Anderson, and S. J. Vainisi (1983)
Arch Ophthalmol 101, 1597-1603
 |  Abstract »  |  PDF »

Immunophagocytic properties of retinal pigment epithelium cells.

V. Elner, T Schaffner, K Taylor, and S Glagov (1981)
Science 211, 74-76
 |  Abstract »  |  PDF »

Phagocytosis in the retinal pigment epithelium of the RCS rat.

A. Goldman and P. O'Brien (1978)
Science 201, 1023-1025
 |  Abstract »  |  PDF »

Defective phagocytosis of isolated rod outer segments by RCS rat retinal pigment epithelium in culture.

R. Edwards and R. Szamier (1977)
Science 197, 1001-1003
 |  Abstract »  |  PDF »

Correction of the retinal dystrophy phenotype of the RCS rat by viral gene transfer of Mertk.

D. Vollrath, W. Feng, J. L. Duncan, D. Yasumura, P. M. D'Cruz, A. Chappelow, M. T. Matthes, M. A. Kay, and M. M. LaVail (2001)
PNAS 98, 12584-12589
 |  Abstract »  |  Full Text »  |  PDF »

To Advertise   |   Find Products