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Science 30 April 1976:
Vol. 192. no. 4238, pp. 483 - 485
DOI: 10.1126/science.1257783
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Articles

Science, Vol 192, Issue 4238, 483-485
Copyright © 1976 by American Association for the Advancement of Science

articles

Neuronal substrate of classical conditioning in the hippocampus

TW Berger, B Alger, and RF Thompson

Neuronal activity in dorsal hippocampus was recorded in rabbits-during classical conditioning of nictitating membrane response, with tone as conditioned stimulus and corneal air puff as unconditioned stimulus. Unit activity in hippocampus rapidly forms a temporal neuronal "model" of the behavioral response early in training. This hippocampal response does not develop in control animals given unpaired stimuli.


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