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Science 19 March 1976:
Vol. 191. no. 4232, pp. 1189 - 1190
DOI: 10.1126/science.1257744
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Articles

Science, Vol 191, Issue 4232, 1189-1190
Copyright © 1976 by American Association for the Advancement of Science

articles

Human Y-chromosome-specific reiterated DNA

LM Kunkel, KD Smith, and SH Boyer

Radiolabeled reiterated DNA specific for the human Y chromosome has been obtained by extensive reassociations between [3H]DNA prepared from men and excess DNA from women. These highly purifed labeled sequences reassociate only with DNA from individuals with a Y chromosome. The percentage of Y-chromosome-specific DNA isolated from individuals with differing numbers of Y chromosomes is a function of the number of chromosomes present. The purifed Y-chromosome-specific sequences may represent between 7 and 11 percent of the human Y chromosome.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Sex Reversal: Deletion Mapping the Male-determining Function of the Human Y Chromosome.
D.C. Page (1986)
Cold Spring Harb Symp Quant Biol 51, 229-235
   Abstract »    PDF »
Mammalian gonadal determination and gametogenesis.
J. Gordon and F. Ruddle (1981)
Science 211, 1265-1271
   Abstract »    PDF »
The status of the gene map of the human chromosomes.
V. McKusick and F. Ruddle (1977)
Science 196, 390-405
   Abstract »    PDF »


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