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Science 19 March 1976:
Vol. 191. no. 4232, pp. 1187 - 1189
DOI: 10.1126/science.1257743
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Articles

Science, Vol 191, Issue 4232, 1187-1189
Copyright © 1976 by American Association for the Advancement of Science

articles

Lateral preoptic lesions in rats separate urge to drink from amount of water drunk

MH Teicher and EM Blass

Rats with bilaterally symmetrical lesions in the laterla preoptic area do not drink after acute intracellular dehydration, but they drink normally after water deprivation. They, like normal rats, also drink more when cellular dehydration is superimposed upon water deprivation. Unlike normal rats, however, rats with lesions in the lateral preoptic area do not increase their rate of lever-pressing in response to the combined stimulus. Thus, the urge to drink can be separated from the amount of fluid drunk.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)