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Science 19 March 1976:
Vol. 191. no. 4232, pp. 1183 - 1185
DOI: 10.1126/science.769158
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Articles

Science, Vol 191, Issue 4232, 1183-1185
Copyright © 1976 by American Association for the Advancement of Science

articles

Phylogeny of DNA polymerase-beta

LM Chang

Analyses of various organisms for DNA polymerase-beta activity show that the enzyme is widely distributed in cells from multicellular animals but absent in bacteria, plants, and protozoa. These results suggest that DNA polymerase-beta may have evolved with the development of metazoan forms. Further evolutionary changes of the enzyme protein may account for some of the minor differences in properties of the enzyme in various organisms.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
DNA polymerases in parasitic protozoans differ from host enzymes.
L. Chang, E Cheriathundam, E. Mahoney, and A Cerami (1980)
Science 208, 510-511
   Abstract »    PDF »
A Stimulatory Factor for Yeast DNA Polymerase.
L. M. S. Chang, K. Lurie, and P. Plevani (1979)
Cold Spring Harb Symp Quant Biol 43, 587-595
   Abstract »    PDF »


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