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Science 27 February 1976:
Vol. 191. no. 4229, pp. 861 - 862
DOI: 10.1126/science.1251199
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Articles

Science, Vol 191, Issue 4229, 861-862
Copyright © 1976 by American Association for the Advancement of Science

articles

Nicotinic acid reduction of plasma volume loss after thermal trauma

JG Hilton and CH Wells

Intravenous administration of nicotinic acid to the anesthetized dog prior to thermal trauma reduced plasma loss at 10 minutes after burn from 7 milliliters per kilogram to less than 2 millimeters per kilogram. During the next 50 minutes plasma loss was the same in treated and untreated animals. An additional dose of nicotinic acid 30 minutes after burn prevented this further loss.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)