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Science 30 January 1976:
Vol. 191. no. 4225, pp. 401 - 402
DOI: 10.1126/science.1246624

Articles

Science, Vol 191, Issue 4225, 401-402
Copyright © 1976 by American Association for the Advancement of Science


articles

Wheat gluten as a pathogenic factor in schizophrenia

MM Singh and Kay SR

Schizophrenics maintained on a cereal grain-free and milk-free diet and receiving optimal treatment with neuropleptics showed an interruption or reversal of their therapeutic progress during a period of "blind" wheat gluten challenge. The exacerbation of the disease process was not due to variations in neuroleptic doses. After termination of the gluten challenge, the course of improvement was reinstated. The observed effects seemed to be due to a primary schizophrenia-promoting effect of wheat gluten.


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