Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 16 January 1976:
Vol. 191. no. 4223, pp. 204 - 205
DOI: 10.1126/science.1857
Prev | Table of Contents | Next

Articles

Science, Vol 191, Issue 4223, 204-205
Copyright © 1976 by American Association for the Advancement of Science

articles

Specific effects of neurotransmitter antagonists on ganglion cells in rabbit retina

HJ Wyatt and NW Day

Directionally sensitive ganglion cells in rabbit retina lose their directional sensitivity when picrotoxin, an antagonist of the inhibitory neurotransmitter gamma-aminobutyric acid, is infused into the retinal blood supply. Strychnine, an antagonist of glycine, does not produce this effect. Other receptive field types are affected by strychnine but not picrotoxin. Inhibitory transmitters therefore have specific functions in information processing in the retina.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Synaptic physiology of direction selectivity in the retina.
Z. J. Zhou and S. Lee (2008)
J. Physiol. 586, 4371-4376
   Abstract »    Full Text »    PDF »
ON direction-selective ganglion cells in the mouse retina.
W. Sun, Q. Deng, W. R. Levick, and S. He (2006)
J. Physiol. 576, 197-202
   Abstract »    Full Text »    PDF »
Identification of ON-OFF direction-selective ganglion cells in the mouse retina.
S. Weng, W. Sun, and S. He (2005)
J. Physiol. 562, 915-923
   Abstract »    Full Text »    PDF »
A Unique Role for Kv3 Voltage-Gated Potassium Channels in Starburst Amacrine Cell Signaling in Mouse Retina.
A. Ozaita, J. Petit-Jacques, B. Volgyi, C. S. Ho, R. H. Joho, S. A. Bloomfield, and B. Rudy (2004)
J. Neurosci. 24, 7335-7343
   Abstract »    Full Text »    PDF »
Asymmetric Temporal Properties in the Receptive Field of Retinal Transient Amacrine Cells.
K. Djupsund, T. Furukawa, S. Yasui, and M. Yamada (2003)
J. Gen. Physiol. 122, 445-458
   Abstract »    Full Text »    PDF »
Diverse Synaptic Mechanisms Generate Direction Selectivity in the Rabbit Retina.
W. R. Taylor and D. I. Vaney (2002)
J. Neurosci. 22, 7712-7720
   Abstract »    Full Text »    PDF »
Dendritic Computation of Direction Selectivity by Retinal Ganglion Cells.
W. R. Taylor, S. He, W. R. Levick, and D. I. Vaney (2000)
Science 289, 2347-2350
   Abstract »    Full Text »
Calcium Released From Intracellular Stores Inhibits GABAA-Mediated Currents in Ganglion Cells of the Turtle Retina.
A. Akopian, R. Gabriel, and P. Witkovsky (1998)
J Neurophysiol 80, 1105-1115
   Abstract »    Full Text »    PDF »
GABAergic Inhibition Influences Auditory Motion-Direction Sensitivity in Barn Owls.
D. Kautz and H. Wagner (1998)
J Neurophysiol 80, 172-185
   Abstract »    Full Text »    PDF »
Directionality and Inhibition in Crayfish Tangential Cells.
R. M. Glantz (1998)
J Neurophysiol 79, 1157-1166
   Abstract »    Full Text »    PDF »
Dendritic Computation of Direction Selectivity and Gain Control in Visual Interneurons.
S. Single, J. Haag, and A. Borst (1997)
J. Neurosci. 17, 6023-6030
   Abstract »    Full Text »    PDF »
Pharmacology of Directionally Selective Ganglion Cells in the Rabbit Retina.
C. A. Kittila and S. C. Massey (1997)
J Neurophysiol 77, 675-689
   Abstract »    Full Text »    PDF »
Computational neuroscience.
T. Sejnowski, C Koch, and P. Churchland (1988)
Science 241, 1299-1306
   Abstract »    PDF »
Amacrine cells in Necturus retina: evidence for independent gamma-aminobutyric acid- and glycine-releasing neurons.
R. Miller, R. Dacheux, and T. Frumkes (1977)
Science 198, 748-750
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)