Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 16 January 1976:
Vol. 191. no. 4223, pp. 187 - 188
DOI: 10.1126/science.1246606
Prev | Table of Contents | Next

Articles

Science, Vol 191, Issue 4223, 187-188
Copyright © 1976 by American Association for the Advancement of Science

articles

Sulfoxide reduction in relation to organophosphorus insecticide detoxification

DeBaun JR and JJ Menn

Carbophenothion sulfoxide, an oxidative metabolite of carbophenothion, is reduced to carbophenothion in the living rat and by an in vitro system containing rat liver enzyme, reduced nicotinamide adenine dinucleotide phosphate, and flavin adenine dinu cleotide phosphate. Reduction of sulfoxides, formed metabolicially from certain commercial organophosphorus insecticides, may be important in ameliorating the toxicity of these compounds.




To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)