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Science 15 August 1975: Vol. 189. no. 4202, pp. 561 - 563 DOI: 10.1126/science.1145213
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Articles
Science, Vol 189, Issue 4202, 561-563
Copyright © 1975 by American Association for the Advancement of Science
Erythrocyte receptors for (Plasmodium knowlesi) malaria: Duffy blood group determinants
LH Miller,
SJ Mason,
JA Dvorak,
MH McGinniss,
and
IK Rothman
Duffy blood group negative human erythrocytes (FyFy) are resistant to infection by Plasmodium knowlesi, a simian malaria that infects Duffy positive human erythrocytes. The P. knowlesi resistance factor, Duffy negative erythrocytes, occurs in high frequency in West Africa, where the people are resistant to vivax malaria. This suggests that Duffy blood group determinants (Fya or Fyb) may be erythrocyte receptors for P. vivax.
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