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Science 27 June 1975:
Vol. 188. no. 4195, pp. 1312 - 1314
DOI: 10.1126/science.1145197
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Articles

Science, Vol 188, Issue 4195, 1312-1314
Copyright © 1975 by American Association for the Advancement of Science

articles

Visual membranes: specificity of fatty acid precursors for the electrical response to illumination

TG Wheeler, RM Benolken, and RE Anderson

Rat electroretinograms were measured as a function of dietary supplements of purified ethyl esters of linolenic acid, linoleic acid, and oleic acid. Polyunsaturated fatty acids derived from precursors of linolenic and linoleic acids appear to be important functional components of photoreceptor cell membranes, although in equal dietary concentrations, linolenic acid precursors affect electroretinogram amplitudes to a greater extent than linoleic acid precursors. The electrical response of photoreceptor cell membranes appears to be a function of the position of the double bonds as well as a function of the total number of double bonds in fatty acid supplements.


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