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Science 31 January 1975:
Vol. 187. no. 4174, pp. 359 - 361
DOI: 10.1126/science.1167426
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Articles

Science, Vol 187, Issue 4174, 359-361
Copyright © 1975 by American Association for the Advancement of Science

articles

Growth, behavior, and brain catecholamines in lead-exposed neonatal rats: a reappraisal

M Golter and IA Michaelson

Daily oral administration of lead to newborn rats has no adverse effect on their body growth. Lead-treated rats were more active than age-matched controls. Endogenous levels of brain dopamine were unchanged, whereas norepinephrine was increased, suggesting a possible relationship between lead exposure during earliest developmental periods, increased motor activity, and brain norepinephrine, and not brain dopamine as previously postulated.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
The Behavioral Effects of Prenatal and Early Postnatal Lead Exposure in the Primate Ma Ca Ca Fascicularis.
D. L. Hopper, W. J. Kernan, and W. E. Lloyd (1986)
Toxicology and Industrial Health 2, 1-16
   Abstract »    PDF »
Lead exposure during infancy permanently increases lithium-induced polydipsia.
R. Mailman, M. Krigman, R. Mueller, P Mushak, and G. Breese (1978)
Science 201, 637-639
   Abstract »    PDF »
Lead poisoning: altered urinary catecholamine metabolites as indicators of intoxication in mice and children.
E. Silbergeld and J. Chisolm Jr (1976)
Science 192, 153-155
   Abstract »    PDF »


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