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Science 8 November 1974:
Vol. 186. no. 4163, pp. 540 - 542
DOI: 10.1126/science.186.4163.540
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Articles

Sex-Dependent Behavioral Effects of Cerebral Cortical Lesions in the Developing Rhesus Monkey

Patricia S. Goldman 1, Howard T. Crawford 1, Linton P. Stokes 1, Thelma W. Galkin 1, and H. Enger Rosvold 1

1 Section Neuropsychology, Laboratory of Psychology, National Institute of Mental Health, Bethesda, Maryland 20014

Male rhesus monkeys with orbital prefrontal lesions were imtpaired on behavioral tests at 2frac12 months of age whereas similar deficits were not detected in females with comparable lesions until 15 to 18 months of age. The results suggest that the maturation of a cortical region in the primate brain proceeds at different tempos in males and females.


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