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Science 2 August 1974:
Vol. 185. no. 4149, pp. 447 - 449
DOI: 10.1126/science.185.4149.447
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Articles

Anemia in Domestic Cats: Effect on Hemoglobin Components and Whole Blood Oxygenation

A. G. Mauk 1, H. T. Whelan 1, G. R. Putz 1, and F. Taketa 1

1 Department of Biochemistry, Medical College of Wisconsin, Milwaukee 53233

Phenylhydrazine-induced anemia in the domestic cat results in an increase in minor, high oxygen affinity hemoglobin B components and an accompanying decrease in the major, low affinity B component. This change is accompanied by an unusually large increase in erythrocytic adenosine triphosphate and 2,3-diphosphoglycerate, a slight decrease in the oxygen affinity of whole blood, and a large decrease in the Hill constant.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)