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Science 26 July 1974:
Vol. 185. no. 4148, pp. 368 - 370
DOI: 10.1126/science.185.4148.368
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Articles

Platelet and Plasma Fibrinogens Are Identical Gene Products

R. F. Doolittle 1, T. Takagi 1, and B. A. Cottrell 1

1 Department of Chemistry, University of California, San Diego, La Jolla 92037

Human platelet fibrinogen has been shown to be indistinguishable from plasma fibrinogen by a variety of criteria, including subunit composition and cross-linking characteristics as judged by sodium dodecyl sulfate-gel electro phoresis, quantitative amino terminal analysis of fibrin, and the amino acid compositions of fibrinopeptides released from platelet and plasma fibrinogens is products of the same gene or genes.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Identification of thrombin activatable fibrinolysis inhibitor (TAFI) in human platelets.
L. O. Mosnier, P. Buijtenhuijs, P. F. Marx, J. C. M. Meijers, and B. N. Bouma (2003)
Blood 101, 4844-4846
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Protein C Inhibitor Secreted from Activated Platelets Efficiently Inhibits Activated Protein C on Phosphatidylethanolamine of Platelet Membrane and Microvesicles.
J. Nishioka, M. Ning, T. Hayashi, and K. Suzuki (1998)
J. Biol. Chem. 273, 11281-11287
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