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Articles
Microbodies (Peroxisomes) Containing Catalase in Myocardium: Morphological and Biochemical Evidence
1 Harvard Pathology Unit, Mallory Institute of Pathology, Boston City Hospital, Boston, Massachusetts 02118
Microbodies characterized by a single limiting membrane and finely granular matrix occur in mouse myocardium and appear in close spatial relation to mitochondria and sarcoplasmic reticulum. The presence of catalase in the microbodies is revealed cytochemically and confirmed biochemically by direct measurement of its activity in myocardial tissue fractions. It is suggested that the microbodies may play an important role in myocardial lipid metabolism.
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Science. ISSN 0036-8075 (print), 1095-9203 (online)