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Science 1 March 1974:
Vol. 183. no. 4127, pp. 857 - 859
DOI: 10.1126/science.183.4127.857
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Articles

Penetration of Somatic Mammalian Cells by Sperm

Aaron Bendich 1, Ellen Borenfreund 1, and Stephen S. Sternberg 1

1 Laboratory of Cell Biochemistry, Memorial Sloan-Kettering Cancer Center, New York 10021

Penetration of somatic mammalian cells by spermatozoa occurred after simple admixture in culture. With sperm labeled in vivo, autoradiography revealed incorporation of DNA into nuclei of recipient cells, indicating release of DNA after entrance by sperm. This system provides a new approach to study the molecular biology of information transfer and of haploid gene expression.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Endogenous Mammary Tumor Viruses in Mice.
P. Bentvelzen (1974)
Cold Spring Harb Symp Quant Biol 39, 1145-1150
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Science. ISSN 0036-8075 (print), 1095-9203 (online)