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Science 21 December 1973:
Vol. 182. no. 4118, pp. 1253 - 1254
DOI: 10.1126/science.182.4118.1253
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Articles

Membrane Fatty Acids Associated with the Electrical Response in Visual Excitation

R. M. Benolken 1, Robert E. Anderson 2, and Thomas G. Wheeler 3

1 University of Texas, Graduate School of Biomedical Sciences, Texas Medical Center, Houston 77025
2 Depatrment of Ophthalmology, Baylor College of Medicine, Texas Medical Center
3 University of Texas, Graduate School of Biomedical Sciences

The fatty acid composition of rat photoreceptor membranes was altered by dietary manipulation. A functional alteration was also observed in the component of the electroretinogram which is generated by the photoreceptors. A membrane fatty acid, docosahexaenoic acid, appears to be involved in the transduction process of visual excitation.


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