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Science 23 November 1973:
Vol. 182. no. 4114, pp. 843 - 845
DOI: 10.1126/science.182.4114.843
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Articles

Aplysia Giant Cell: Soma-Axon Voltage Clamp Current Differences

R. T. Kado 1

1 Department of Physiology, School of Medicine, University of California, Los Angeles 90024, and Laboratoire de Neurobiologie Cellulaire, CNRS, 91190 Gif sur Yvette, France

Under voltage clamp, local membrane currents have been measured in several regions of the soma. The early inward current appears to pass largely through the membrane of the axon and of the soma near the axon in normal media. After 10-5 molar tetrodotoxin (TTX) is added to the bathing medium the larger inward current is found in the somatic membrane away from the axon. The late currents are larger at the soma in both normal and TTX media.


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