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Science 7 September 1973:
Vol. 181. no. 4103, pp. 941 - 943
DOI: 10.1126/science.181.4103.941
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Articles

Mouse Immunoglobulin Kappa Chain MPC 11: Extra Amino-Terminal Residues

George P. Smith 1

1 Departments of Genetics and Medical Genetics, University of Wisconsin, Madison 53706

The kappa chain from the immunoglobulin of myeloma tumor MPC 11 has 12 extra residues at its amino terminus, the first six of which are identical to the residues at positions 1 to 6 of typical mouse kappa chains and at positionss 13 to 18 of MPC 11 itself. Two of the peptide bonds within this extra 12-residue segment are cleaved under very mild conditions.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Partial amino acid sequence of the precursor of immunoglobulin light chain programmed by messenger RNA in vitro.
I Schechter (1975)
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Immunoglobulin Genes: Arranged in Tandem or in Parallel?.
O. Smithies (1974)
Cold Spring Harb Symp Quant Biol 38, 725-737
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Immunoglobulin Genes: A Test of Somatic Vs. Germ Line Hypothesis by RNA/DNA Hybridization.
T. Delovitch and C. Baglioni (1974)
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