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Science 22 June 1973:
Vol. 180. no. 4092, pp. 1297 - 1298
DOI: 10.1126/science.180.4092.1297
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Articles

Heart Muscle Viability following Hypoxia: Protective Effect of Acidosis

Oscar H. L. Bing 1, Wesley W. Brooks 1, and Joseph V. Messer 1

1 Tufts Circulation Laboratory, Boston City Hospital, Boston, Massachusetts 02118

The mechanical performance of hypoxic heart muscle is further depressed by an acid pH. In contrast to preparations at normal or alkaline pH. however, hypoxic preparations at acid pH do not develop contracture and exhibit full recovery of mechanical activity upon reoxygenation.


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