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Science 23 March 1973:
Vol. 179. no. 4079, pp. 1236 - 1238
DOI: 10.1126/science.179.4079.1236
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Articles

Oxygen Dissociation in Human Erythrocytes: Its Response to Hyperbaric Environments

L. A. Kiesow 1, J. W. Bless 1, and J. B. Shelton 1

1 Experimental Medicine Division, Naval Medical Research Institute, Bethesda, Maryland 20014

Hyperbaric nitrogen at a pressure of 100 atmospheres increases significantly the affinity of erythrocytic hemoglobin for oxygen. This results in oxygen dissociation curves which are shifted to lower than normal oxygen partial pressures. The pressure effect is completely reversible and can therefore be observed only during exposure of the blood cells to the hyperbaric gas.


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Science. ISSN 0036-8075 (print), 1095-9203 (online)