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Science 16 March 1973:
Vol. 179. no. 4078, pp. 1129 - 1131
DOI: 10.1126/science.179.4078.1129
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Articles

Chromosome Assignments in Man of the Genes for Two Hexosephosphate Isomerases

F. A. McMorris 1, T. R. Chen 1, F. Ricciuti 1, J. Tischfield 1, R. Creagan 1, and F. Ruddle 1

1 Department of Biology, Yale University, New Haven, Connecticut 06520

Thirty-seven clones of somatic cell hybrids between human and mouse cells were examined for retention of human chromosomes and expression of human constitutive enzymes. Human glucosephosphate isomerase and chromosome F-19 were retained or lost concordantly, as were human mannosephosphate isomerase and chromosome C-7. The genes for the enzymes are thus assigned to these two chromosomes.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Human Serum Albumin Phenotype Activation in Mouse Hepatoma-Human Leukocyte Cell Hybrids.
G. J. Darlington, H. P. Bernhard, and F. H. Ruddle (1974)
Science 185, 859-862
   Abstract »    PDF »
Genetics of Cell Transformation by Simian Virus 40.
C. M. Croce, K. Huebner, A. J. Girardi, and H. Koprowski (1974)
Cold Spring Harb Symp Quant Biol 39, 335-343
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)