Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 16 March 1973:
Vol. 179. no. 4078, pp. 1126 - 1129
DOI: 10.1126/science.179.4078.1126
Prev | Table of Contents | Next

Articles

DNA Content and DNA-Based Centromeric Index of the 24 Human Chromosomes

Mortimer L. Mendelsohn 1, Brian H. Mayall 1, Elliot Bogart 1, Dan H. Moore II 1, and Benson H. Perry 1

1 Department of Radiology, University of Pennsylvania, Philadelphia 19104

The chromosomes of two human males were identified by fluorescent banding, restained, and measured by scanning microscopy and computer analysis. The two variables, DNA content and DNA-based centromeric index, provided almost complete discrimination of chromosome types. Some chromosomes showed significant differences in DNA content between the men, and for one man two pairs of chromosomes showed significant differences between homologs.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Comparison of AluI-induced frequencies of dicentrics and translocations in human lymphocytes by chromosome painting.
S. Chatterjee, W. Martinez-Lopez, M. Grigorova, F. Darroudi, G. Obe, and A.T. Natarajan (1999)
Mutagenesis 14, 283-286
   Abstract »    Full Text »    PDF »
Cytogenetic Analysis by In Situ Hybridization with Fluorescently Labeled Nucleic Acid Probes.
D. Pinkel, J.W. Gray, B. Trask, G. van den Engh, J. Fuscoe, and H. van Dekken (1986)
Cold Spring Harb Symp Quant Biol 51, 151-157
   Abstract »    PDF »
Applications of Rapid Single-Cell Analysis to Perinatal Medicine and Pediatrics.
R. A. DOHERTY and P. K. HORAN (1978)
Arch Pediatr Adolesc Med 132, 556-559
   Abstract »    PDF »
A Direct Approach to the Structure of Eukaryotic Chromosomes.
J. Sedat and L. Manuelidis (1978)
Cold Spring Harb Symp Quant Biol 42, 331-350
   Abstract »    PDF »
Higher-order Structure of Mitotic Chromosomes.
A. Leth Bak and J. Zeuthen (1978)
Cold Spring Harb Symp Quant Biol 42, 367-377
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)