Science 5 January 1973: Vol. 179. no. 4068, pp. 77 - 79 DOI: 10.1126/science.179.4068.77

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Articles

The RAPID Method for Blood Processing Yields New Insight in Plasma Concentrations and Molecular Forms of Circulating Gut Peptides.

A. Stengel, D. Keire, M. Goebel, L. Evilevitch, B. Wiggins, Y. Tache, and J. R. Reeve Jr. (2009)
Endocrinology 150, 5113-5118
 |  Abstract »  |  Full Text »  |  PDF »

Inhibitory Effect of Somatostatin-14 on L-Type Voltage-Gated Calcium Channels in Cultured Cone Photoreceptors Requires Intracellular Calcium.

K. Jian, R. Barhoumi, M. L. Ko, and G. Y.-P. Ko (2009)
J Neurophysiol 102, 1801-1810
 |  Abstract »  |  Full Text »  |  PDF »

Effects of Somatostatin Analogs on Glucose Homeostasis: A Metaanalysis of Acromegaly Studies.

G. Mazziotti, I. Floriani, S. Bonadonna, V. Torri, P. Chanson, and A. Giustina (2009)
J. Clin. Endocrinol. Metab. 94, 1500-1508
 |  Abstract »  |  Full Text »  |  PDF »

Total Gastrectomy Causes a Sustained, Long-term Elevation of Somatostatin in Plasma, Independent of the Mode of Reconstruction in Pigs.

U. SMEDH, L. HANSSON, R. EKMAN, and T. ZILLING (2009)
In Vivo 23, 99-103
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Neuronostatin Encoded by the Somatostatin Gene Regulates Neuronal, Cardiovascular, and Metabolic Functions.

W. K. Samson, J. V. Zhang, O. Avsian-Kretchmer, K. Cui, G. L. C. Yosten, C. Klein, R.-M. Lyu, Y. X. Wang, X. Q. Chen, J. Yang, et al. (2008)
J. Biol. Chem. 283, 31949-31959
 |  Abstract »  |  Full Text »  |  PDF »

Circulating markers for endocrine tumours of the gastroenteropancreatic tract.

J. E S Ardill (2008)
Ann Clin Biochem 45, 539-559
 |  Abstract »  |  Full Text »  |  PDF »

Expression of Somatostatin and Somatostatin Receptor Subtypes 1-5 in Human Normal and Diseased Kidney.

S. Bhandari, N. Watson, E. Long, S. Sharpe, W. Zhong, S.-Z. Xu, and S. L. Atkin (2008)
J. Histochem. Cytochem. 56, 733-743
 |  Abstract »  |  Full Text »  |  PDF »

Effect of Intravitreal Administration of Somatostatin and sst2 Analogs on AMPA-Induced Neurotoxicity in Rat Retina.

F. Kiagiadaki and K. Thermos (2008)
Invest. Ophthalmol. Vis. Sci. 49, 3080-3089
 |  Abstract »  |  Full Text »  |  PDF »

The Effect of Transforming Growth Factor {beta} on Human Neuroendocrine Tumor BON Cell Proliferation and Differentiation Is Mediated through Somatostatin Signaling.

F. P. Leu, M. Nandi, and C. Niu (2008)
Mol. Cancer Res. 6, 1029-1042
 |  Abstract »  |  Full Text »  |  PDF »

Activation of GIRK channels in substantia gelatinosa neurones of the adult rat spinal cord: a possible involvement of somatostatin.

T. Nakatsuka, T. Fujita, K. Inoue, and E. Kumamoto (2008)
J. Physiol. 586, 2511-2522
 |  Abstract »  |  Full Text »  |  PDF »

The Role of Nitric Oxide and cGMP in Somatostatin's Protection against Retinal Ischemia.

N. Mastrodimou, F. Kiagiadaki, and K. Thermos (2008)
Invest. Ophthalmol. Vis. Sci. 49, 342-349
 |  Abstract »  |  Full Text »  |  PDF »

Spontaneous hypersensitivity in mesenteric afferent nerves of mice deficient in the sst2 subtype of somatostatin receptor.

W. Rong, W. J. Winchester, and D. Grundy (2007)
J. Physiol. 581, 779-786
 |  Abstract »  |  Full Text »  |  PDF »

The Role of {alpha}-Cell Dysregulation in Fasting and Postprandial Hyperglycemia in Type 2 Diabetes and Therapeutic Implications.

B. E. Dunning and J. E. Gerich (2007)
Endocr. Rev. 28, 253-283
 |  Abstract »  |  Full Text »  |  PDF »

Coexpression of Somatostatin Receptor Subtype 5 Affects Internalization and Trafficking of Somatostatin Receptor Subtype 2.

N. Sharif, L. Gendron, J. Wowchuk, P. Sarret, J. Mazella, A. Beaudet, and T. Stroh (2007)
Endocrinology 148, 2095-2105
 |  Abstract »  |  Full Text »  |  PDF »

Somatostatin regulates hepatic growth hormone sensitivity by internalizing growth hormone receptors and by decreasing transcription of growth hormone receptor mRNAs.

N. M. Very and M. A. Sheridan (2007)
Am J Physiol Regulatory Integrative Comp Physiol 292, R1956-R1962
 |  Abstract »  |  Full Text »  |  PDF »

Transient Transcription of the Somatostatin Gene at the Time of Estrogen-Dependent Organization of the Sexually Dimorphic Nucleus of the Rat Preoptic Area.

C. Orikasa, Y. Kondo, and Y. Sakuma (2007)
Endocrinology 148, 1144-1149
 |  Abstract »  |  Full Text »  |  PDF »

Microinjection of exogenous somatostatin in the dorsal vagal complex inhibits pancreatic secretion via somatostatin receptor-2 in rats.

Z. Liao, Z.-S. Li, Y. Lu, and W.-Z. Wang (2007)
Am J Physiol Gastrointest Liver Physiol 292, G746-G752
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of Somatostatin Receptor Subtype-Specific Regulation of Insulin and Glucagon Secretion: An in Vitro Study on Isolated Human Pancreatic Islets.

V. Singh, M. D. Brendel, S. Zacharias, S. Mergler, H. Jahr, B. Wiedenmann, R. G. Bretzel, U. Plockinger, and M. Z. Strowski (2007)
J. Clin. Endocrinol. Metab. 92, 673-680
 |  Abstract »  |  Full Text »  |  PDF »

Interferon-{alpha} and somatostatin analog in patients with gastroenteropancreatic neuroendocrine carcinoma: single agent or combination?.

N Fazio, F de Braud, G Delle Fave, and K Oberg (2007)
Ann. Onc. 18, 13-19
 |  Abstract »  |  Full Text »  |  PDF »

Somatostatin Regulates Aggressive Behavior in an African Cichlid Fish.

B. C. Trainor and H. A. Hofmann (2006)
Endocrinology 147, 5119-5125
 |  Abstract »  |  Full Text »  |  PDF »

Somatostatin Treatment Attenuates Proteinuria and Prevents Weight Loss in NZB/W F1 Mice.

D Paran, J Bernheim, I Golan, D Caspi, J Bernheim, and S Benchetrit (2006)
Lupus 15, 526-531
 |  Abstract »  |  PDF »

Insulin-sensitizing agents in polycystic ovary syndrome..

R. Pasquali and A. Gambineri (2006)
Eur. J. Endocrinol. 154, 763-775
 |  Abstract »  |  Full Text »  |  PDF »

A Dominant-Negative Human Growth Hormone-Releasing Hormone (GHRH) Receptor Splice Variant Inhibits GHRH Binding.

A. T. McElvaine and K. E. Mayo (2006)
Endocrinology 147, 1884-1894
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin-1{beta} and tumor necrosis factor-{alpha} mediation of endotoxin action on growth hormone.

J. A. Daniel, T. H. Elsasser, A. Martinez, B. Steele, B. K. Whitlock, and J. L. Sartin (2005)
Am J Physiol Endocrinol Metab 289, E650-E657
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Distinct functional properties of native somatostatin receptor subtype 5 compared with subtype 2 in the regulation of ACTH release by corticotroph tumor cells.

J. van der Hoek, M. Waaijers, P. M. van Koetsveld, D. Sprij-Mooij, R. A. Feelders, H. A. Schmid, P. Schoeffter, D. Hoyer, D. Cervia, J. E. Taylor, et al. (2005)
Am J Physiol Endocrinol Metab 289, E278-E287
 |  Abstract »  |  Full Text »  |  PDF »

Efficacy of Octreotide-LAR in Dieting Women with Abdominal Obesity and Polycystic Ovary Syndrome.

A. Gambineri, L. Patton, R. De Iasio, B. Cantelli, G. E. Cognini, M. Filicori, A. Barreca, E. Diamanti-Kandarakis, U. Pagotto, and R. Pasquali (2005)
J. Clin. Endocrinol. Metab. 90, 3854-3862
 |  Abstract »  |  Full Text »  |  PDF »

Hypothalamic hormones a.k.a. hypothalamic releasing factors.

R. Guillemin (2005)
J. Endocrinol. 184, 11-28
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Superagonism at the Human Somatostatin Receptor Subtype 4.

M. Engstrom, J. Tomperi, K. El-Darwish, M. Ahman, J.-M. Savola, and S. Wurster (2005)
J. Pharmacol. Exp. Ther. 312, 332-338
 |  Abstract »  |  Full Text »  |  PDF »

Chromosomal localization of three somatostatin genes in zebrafish. Evidence that the [Pro2]-somatostatin-14 isoform and cortistatin are encoded by orthologous genes.

H. Tostivint, L. Joly, I. Lihrmann, M. Ekker, and H. Vaudry (2004)
J. Mol. Endocrinol. 33, R1-R8
 |  Abstract »  |  Full Text »  |  PDF »

Exocytosis sensitivity to growth hormone-releasing hormone in subsets of GH cells in rats under different corticosterone conditions. Ultrastructural study using microwave irradiation for fixation and immunocytochemistry.

H. Ozawa, F. Han, and M. Kawata (2004)
J. Endocrinol. 183, 507-515
 |  Abstract »  |  Full Text »  |  PDF »

Somatostatin Is Expressed and Secreted by Human Adipose Tissue upon Infection and Inflammation.

D. Seboek, P. Linscheid, H. Zulewski, I. Langer, M. Christ-Crain, U. Keller, and B. Muller (2004)
J. Clin. Endocrinol. Metab. 89, 4833-4839
 |  Abstract »  |  Full Text »  |  PDF »

Regulation by Estradiol of Hypothalamic Somatostatin Gene Expression: Possible Involvement of Somatostatin in the Control of Luteinizing Hormone Secretion in the Ewe.

D. Pillon, A. Caraty, C. Fabre-Nys, D. Lomet, M. Cateau, and G. Bruneau (2004)
Biol Reprod 71, 38-44
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Effect of Somatostatin on Nitric Oxide Production in Human Retinal Pigment Epithelium Cell Cultures.

A. Vasilaki, T. Papadaki, G. Notas, G. Kolios, N. Mastrodimou, D. Hoyer, M. Tsilimbaris, E. Kouroumalis, I. Pallikaris, and K. Thermos (2004)
Invest. Ophthalmol. Vis. Sci. 45, 1499-1506
 |  Abstract »  |  Full Text »  |  PDF »

Inflammation and Cancer III. Somatostatin and the innate immune system.

Y. Zavros, J. Y. Kao, and J. L. Merchant (2004)
Am J Physiol Gastrointest Liver Physiol 286, G698-G701
 |  Abstract »  |  Full Text »  |  PDF »

A Single-Dose Comparison of the Acute Effects between the New Somatostatin Analog SOM230 and Octreotide in Acromegalic Patients.

J. van der Hoek, W. W. de Herder, R. A. Feelders, A.-J. van der Lely, P. Uitterlinden, V. Boerlin, C. Bruns, K. W. Poon, I. Lewis, G. Weckbecker, et al. (2004)
J. Clin. Endocrinol. Metab. 89, 638-645
 |  Abstract »  |  Full Text »  |  PDF »

The immunohistochemical localisation of somatostatin receptors 1, 2, 3, and 5 in acoustic neuromas.

N D Stafford, L T Condon, M J C Rogers, L Helboe, D A Crooks, and S L Atkin (2004)
J. Clin. Pathol. 57, 168-171
 |  Abstract »  |  Full Text »  |  PDF »

How does Behavior Change the Brain? Multiple Methods to Answer Old Questions.

R. D. Fernald (2003)
Integr. Comp. Biol. 43, 771-779
 |  Abstract »  |  Full Text »  |  PDF »

Role of Gastrointestinal Hormones in the Proliferation of Normal and Neoplastic Tissues.

R. P. Thomas, M. R. Hellmich, C. M. Townsend Jr., and B. M. Evers (2003)
Endocr. Rev. 24, 571-599
 |  Abstract »  |  Full Text »  |  PDF »

Growth Hormone-Releasing Hormone (GHRH) Neurons in GHRH-Enhanced Green Fluorescent Protein Transgenic Mice: A Ventral Hypothalamic Network.

N. Balthasar, P.-F. Mery, C. B. Magoulas, K. E. Mathers, A. Martin, P. Mollard, and I. C. A. F. Robinson (2003)
Endocrinology 144, 2728-2740
 |  Abstract »  |  Full Text »  |  PDF »

Generation of the Melatonin Endocrine Message in Mammals: A Review of the Complex Regulation of Melatonin Synthesis by Norepinephrine, Peptides, and Other Pineal Transmitters.

V. Simonneaux and C. Ribelayga (2003)
Pharmacol. Rev. 55, 325-395
 |  Abstract »  |  Full Text »  |  PDF »

Targeting sst2A Receptor-Expressing Cells in the Rat Hypothalamus through in Vivo Agonist Stimulation: Neuroanatomical Evidence for a Major Role of this Subtype in Mediating Somatostatin Functions.

Z. Csaba, A. Simon, L. Helboe, J. Epelbaum, and P. Dournaud (2003)
Endocrinology 144, 1564-1573
 |  Abstract »  |  Full Text »  |  PDF »

Localization of Messenger Ribonucleic Acids for Somatostatin Receptor Subtypes (sstr1-5) in the Rat Adrenal Gland.

A.-M. O'Carroll (2003)
J. Histochem. Cytochem. 51, 55-60
 |  Abstract »  |  Full Text »  |  PDF »

Expression of IGFBP-3 by Human Retinal Endothelial Cell Cultures: IGFBP-3 Involvement in Growth Inhibition and Apoptosis.

P. E. Spoerri, S. Caballero, S. H. Wilson, L. C. Shaw, and M. B. Grant (2003)
Invest. Ophthalmol. Vis. Sci. 44, 365-369
 |  Abstract »  |  Full Text »  |  PDF »

Somatostatin Receptor Subtype 5 Regulates Insulin Secretion and Glucose Homeostasis.

M. Z. Strowski, M. Kohler, H. Y. Chen, M. E. Trumbauer, Z. Li, D. Szalkowski, S. Gopal-Truter, J. K. Fisher, J. M. Schaeffer, A. D. Blake, et al. (2003)
Mol. Endocrinol. 17, 93-106
 |  Abstract »  |  Full Text »  |  PDF »

AMPA-sst2 somatostatin receptor interaction in rat hypothalamus requires activation of NMDA and/or metabotropic glutamate receptors and depends on intracellular calcium.

S. Peineau, B. Potier, F. Petit, P. Dournaud, J. Epelbaum, and R. Gardette (2003)
J. Physiol. 546, 101-117
 |  Abstract »  |  Full Text »  |  PDF »

Deficit of Somatostatin-Like Immunoreactivity in the Vitreous Fluid of Diabetic Patients: Possible role in the development of proliferative diabetic retinopathy.

R. Simo, A. Lecube, L. Sararols, J. Garcia-Arumi, R. M. Segura, R. Casamitjana, and C. Hernandez (2002)
Diabetes Care 25, 2282-2286
 |  Abstract »  |  Full Text »  |  PDF »

Expression of Somatostatin Receptors 1 and 2 in Human Choroid Plexus and Arachnoid Granulations: Implications for Idiopathic Intracranial Hypertension.

S. E. Katz, D. D. Klisovic, M. S. O'Dorisio, R. Lynch, and M. Lubow (2002)
Arch Ophthalmol 120, 1540-1543
 |  Abstract »  |  Full Text »  |  PDF »

Growth Hormone Receptor Antagonists: Discovery, Development, and Use in Patients with Acromegaly.

J. J. Kopchick, C. Parkinson, E. C. Stevens, and P. J. Trainer (2002)
Endocr. Rev. 23, 623-646
 |  Abstract »  |  Full Text »  |  PDF »

SOM230: A New Somatostatin Peptidomimetic with Potent Inhibitory Effects on the Growth Hormone/Insulin-Like Growth Factor-I Axis in Rats, Primates, and Dogs.

G. Weckbecker, U. Briner, I. Lewis, and C. Bruns (2002)
Endocrinology 143, 4123-4130
 |  Abstract »  |  Full Text »  |  PDF »

The clinical role of somatostatin analogues as antineoplastic agents: much ado about nothing?.

M. Hejna, M. Schmidinger, and M. Raderer (2002)
Ann. Onc. 13, 653-668
 |  Abstract »  |  Full Text »  |  PDF »

A Comparison of the Effects of Pegvisomant and Octreotide on Glucose, Insulin, Gastrin, Cholecystokinin, and Pancreatic Polypeptide Responses to Oral Glucose and a Standard Mixed Meal.

C. Parkinson, W. M. Drake, M. E. Roberts, K. Meeran, G. M. Besser, and P. J. Trainer (2002)
J. Clin. Endocrinol. Metab. 87, 1797-1804
 |  Abstract »  |  Full Text »  |  PDF »

Localization and Regulation of a Functional GHRH Receptor in the Rat Renal Medulla.

C. Boisvert, C. Pare, C. Veyrat-Durebex, A. Robert, S. Dubuisson, G. Morel, and P. Gaudreau (2002)
Endocrinology 143, 1475-1484
 |  Abstract »  |  Full Text »  |  PDF »

Growth hormone, insulin-like growth factor-1 and the aging cardiovascular system.

A. S. Khan, D. C. Sane, T. Wannenburg, and W. E. Sonntag (2002)
Cardiovasc Res 54, 25-35
 |  Abstract »  |  Full Text »  |  PDF »

A pilot study of a long acting somatostatin analogue for the treatment of refractory rheumatoid arthritis.

D Paran, O Elkayam, A Mayo, H Paran, M Amit, M Yaron, and D Caspi (2001)
Ann Rheum Dis 60, 888-891
 |  Abstract »  |  Full Text »  |  PDF »

Somatostatin Receptor Imaging: Current Status and Future Perspectives.

K. H. Bohuslavizki (2001)
J. Nucl. Med. 42, 1057-1058
 |  Full Text »  |  PDF »

NADPH-Diaphorase Colocalization with Somatostatin Receptor Subtypes sst2A and sst2B in the Retina.

A. Vasilaki, R. Gardette, J. Epelbaum, and K. Thermos (2001)
Invest. Ophthalmol. Vis. Sci. 42, 1600-1609
 |  Abstract »  |  Full Text »

Cerebral Na concentration, Na appetite and thirst of sheep: influence of somatostatin and losartan.

R. S. Weisinger, J. R. Blair-West, P. Burns, D. A. Denton, and B. Purcell (2001)
Am J Physiol Regulatory Integrative Comp Physiol 280, R686-R694
 |  Abstract »  |  Full Text »  |  PDF »

The Somatomedin Hypothesis: 2001.

D. Le Roith, C. Bondy, S. Yakar, J.-L. Liu, and A. Butler (2001)
Endocr. Rev. 22, 53-74
 |  Abstract »  |  Full Text »

Novel Long-Acting Somatostatin Analog with Endocrine Selectivity: Potent Suppression of Growth Hormone But Not of Insulin.

M. Afargan, E. T. Janson, G. Gelerman, R. Rosenfeld, O. Ziv, O. Karpov, A. Wolf, M. Bracha, D. Shohat, G. Liapakis, et al. (2001)
Endocrinology 142, 477-486
 |  Abstract »  |  Full Text »  |  PDF »

Prolactin: Structure, Function, and Regulation of Secretion.

M. E. Freeman, B. Kanyicska, A. Lerant, and G. Nagy (2000)
Physiol Rev 80, 1523-1631
 |  Abstract »  |  Full Text »  |  PDF »

Preclinical Comparison in AR4-2J Tumor-Bearing Mice of Four Radiolabeled 1,4,7,10-Tetraazacyclododecane-1,4,7,10-Tetraacetic Acid-Somatostatin Analogs for Tumor Diagnosis and Internal Radiotherapy.

S. Froidevaux, A. Heppeler, A. N. Eberle, A.-M. Meier, M. Hausler, C. Beglinger, M. Behe, P. Powell, and H. R. Macke (2000)
Endocrinology 141, 3304-3312
 |  Abstract »  |  Full Text »  |  PDF »

Somatostatin-Induced Regulation of SST2A Receptor Expression and Cell Surface Availability in Central Neurons: Role of Receptor Internalization.

H. Boudin, P. Sarret, J. Mazella, A. Schonbrunn, and A. Beaudet (2000)
J. Neurosci. 20, 5932-5939
 |  Abstract »  |  Full Text »  |  PDF »

Social Status Controls Somatostatin Neuron Size and Growth.

H. A. Hofmann and R. D. Fernald (2000)
J. Neurosci. 20, 4740-4744
 |  Abstract »  |  Full Text »  |  PDF »

Pituitary Adenylate Cyclase-Activating Polypeptide and Its Receptors: From Structure to Functions.

D. Vaudry, B. J. Gonzalez, M. Basille, L. Yon, A. Fournier, and H. Vaudry (2000)
Pharmacol. Rev. 52, 269-324
 |  Abstract »  |  Full Text »  |  PDF »

Distribution, Targeting, and Internalization of the sst4 Somatostatin Receptor in Rat Brain.

M. Schreff, S. Schulz, M. Handel, G. Keilhoff, H. Braun, G. Pereira, M. Klutzny, H. Schmidt, G. Wolf, and V. Hollt (2000)
J. Neurosci. 20, 3785-3797
 |  Abstract »  |  Full Text »  |  PDF »

Perspective: Research Activity of Enteropancreatic and Brain/Central Nervous System Hormones Across Invertebrates and Vertebrates.

S. A. Sower, K. Suzuki, and K. L. Reed (2000)
Integr. Comp. Biol. 40, 165-178
 |  Abstract »  |  Full Text »  |  PDF »

Structure-Function Relationships of the Signaling System for the Somatostatin Peptide Hormone Family.

M. A. Sheridan, J. D. Kittilson, and B. J. Slagter (2000)
Integr. Comp. Biol. 40, 269-286
 |  Abstract »  |  Full Text »  |  PDF »

Involvement of the Sst1 Somatostatin Receptor Subtype in the Intrahypothalamic Neuronal Network Regulating Growth Hormone Secretion: An in Vitro and in Vivo Antisense Study.

C. Lanneau, M. T. Bluet-Pajot, P. Zizzari, Z. Csaba, P. Dournaud, L. Helboe, D. Hoyer, E. Pellegrini, G. S. Tannenbaum, J. Epelbaum, et al. (2000)
Endocrinology 141, 967-979
 |  Abstract »  |  Full Text »  |  PDF »

Somatostatin Inhibits Insulin and Glucagon Secretion via Two Receptor Subtypes: An in Vitro Study of Pancreatic Islets from Somatostatin Receptor 2 Knockout Mice.

M. Z. Strowski, R. M. Parmar, A. D. Blake, and J. M. Schaeffer (2000)
Endocrinology 141, 111-117
 |  Abstract »  |  Full Text »  |  PDF »

Intracellular Dynamics of sst5 Receptors in Transfected COS-7 Cells: Maintenance of Cell Surface Receptors during Ligand-Induced Endocytosis.

T. Stroh, A. C. Jackson, P. Sarret, C. Dal Farra, J.-P. Vincent, H.-J. Kreienkamp, J. Mazella, and A. Beaudet (2000)
Endocrinology 141, 354-365
 |  Abstract »  |  Full Text »  |  PDF »

Cloning of the Mouse Somatostatin Receptor Subtype 5 Gene: Promoter Structure and Function.

D. F. Gordon, W. W. Woodmansee, S. R. Lewis, R. A. James, W. M. Wood, and E. C. Ridgway (1999)
Endocrinology 140, 5598-5608
 |  Abstract »  |  Full Text »

Rainbow trout (Oncorhynchus mykiss) possess two somatostatin mRNAs that are differentially expressed.

C. A. Moore, J. D. Kittilson, M. M. Ehrman, and M. A. Sheridan (1999)
Am J Physiol Regulatory Integrative Comp Physiol 277, R1553-R1561
 |  Abstract »  |  Full Text »  |  PDF »

DOTA-Lanreotide: A Novel Somatostatin Analog for Tumor Diagnosis and Therapy.

P. M. Smith-Jones, C. Bischof, M. Leimer, D. Gludovacz, P. Angelberger, T. Pangerl, M. Peck-Radosavljevic, G. Hamilton, K. Kaserer, A. Kofler, et al. (1999)
Endocrinology 140, 5136-5148
 |  Abstract »  |  Full Text »

Molecular Cloning and Expression of Two Type One Somatostatin Receptors in Goldfish Brain.

X. Lin, J. A. Janovick, S. Brothers, P. M. Conn, and R. E. Peter (1999)
Endocrinology 140, 5211-5219
 |  Abstract »  |  Full Text »

Immunohistochemical Localization of Somatostatin Receptor Subtypes sst1 and sst2 in the Rat Retina.

L. Helboe and M. Moller (1999)
Invest. Ophthalmol. Vis. Sci. 40, 2376-2382
 |  Abstract »  |  Full Text »  |  PDF »

Expression of Three Distinct Somatostatin Messenger Ribonucleic Acids (mRNAs) in Goldfish Brain: Characterization of the Complementary Deoxyribonucleic Acids, Distribution and Seasonal Variation of the mRNAs, and Action of a Somatostatin-14 Variant.

X. Lin, C. J. Otto, and R. E. Peter (1999)
Endocrinology 140, 2089-2099
 |  Abstract »  |  Full Text »

Neuroendocrine Control of Growth Hormone Secretion.

E. E. Muller, V. Locatelli, and D. Cocchi (1999)
Physiol Rev 79, 511-607
 |  Abstract »  |  Full Text »  |  PDF »

Inhibitory and Stimulatory Effects of Somatostatin on Two Human Pancreatic Cancer Cell Lines: A Primary Role for Tyrosine Phosphatase SHP-1.

N. Douziech, E. Calvo, Z. Coulombe, G. Muradia, J. Bastien, R. A. Aubin, A. Lajas, and J. Morisset (1999)
Endocrinology 140, 765-777
 |  Abstract »  |  Full Text »

Rapid Identification of Subtype-Selective Agonists of the Somatostatin Receptor Through Combinatorial Chemistry.

S. P. Rohrer, E. T. Birzin, R. T. Mosley, S. C. Berk, S. M. Hutchins, D. Shen, Y. Xiong, E. C. Hayes, R. M. Parmar, F. Foor, et al. (1998)
Science 282, 737-740
 |  Abstract »  |  Full Text »

The New Biology of Gastrointestinal Hormones.

J. F. REHFELD (1998)
Physiol Rev 78, 1087-1108
 |  Abstract »  |  Full Text »  |  PDF »

Immunohistochemical and Cytochemical Localization of the Somatostatin Receptor Subtype sst1 in the Somatostatinergic Parvocellular Neuronal System of the Rat Hypothalamus.

L. Helboe, C. E. Stidsen, and M. Moller (1998)
J. Neurosci. 18, 4938-4945
 |  Abstract »  |  Full Text »  |  PDF »

Novel Somatostatin Analogs for the Treatment of Acromegaly and Cancer Exhibit Improved In Vivo Stability and Distribution.

T. J. Gillespie, A. Erenberg, S. Kim, J. Dong, J. E. Taylor, V. Hau, and T. P. Davis (1998)
J. Pharmacol. Exp. Ther. 285, 95-104
 |  Abstract »  |  Full Text »

Synthesis and biological evaluation of cytotoxic analogs of somatostatin containing doxorubicin or its intensely potent derivative, 2-pyrrolinodoxorubicin.

A. Nagy, A. V. Schally, G. Halmos, P. Armatis, R.-Z. Cai, V. Csernus, M. Kovacs, M. Koppan, K. Szepeshazi, and Z. Kahan (1998)
PNAS 95, 1794-1799
 |  Abstract »  |  Full Text »  |  PDF »

Interrelationships between Somatostatin sst2A Receptors and Somatostatin-Containing Axons in Rat Brain: Evidence for Regulation of Cell Surface Receptors by Endogenous Somatostatin.

P. Dournaud, H. Boudin, A. Schonbrunn, G. S. Tannenbaum, and A. Beaudet (1998)
J. Neurosci. 18, 1056-1071
 |  Abstract »  |  Full Text »  |  PDF »

The Localization of Messenger Ribonucleic Acids for Somatostatin Receptors 1, 2, and 3 in Rat Testis.

L.-J. Zhu, K. Krempels, C. W. Bardin, A.-M. O'Carroll, and E. Mezey (1998)
Endocrinology 139, 350-357
 |  Abstract »  |  Full Text »  |  PDF »

Placenta-Specific Expression of the Rat Growth Hormone-Releasing Hormone Gene Promoter in Transgenic Mice.

N. Nogues, J. A. Del RIo, M. Perez-Riba, E. Soriano, R. A. Flavell, and A. Boronat (1997)
Endocrinology 138, 3222-3227
 |  Abstract »  |  Full Text »  |  PDF »

Both Overlapping and Distinct Signaling Pathways for Somatostatin Receptor Subtypes SSTR1 and SSTR2 in Pituitary Cells.

L. Chen, V. D. Fitzpatrick, R. L. Vandlen, and A. H. Tashjian Jr. (1997)
J. Biol. Chem. 272, 18666-18672
 |  Abstract »  |  Full Text »  |  PDF »

Somatostatin Inhibits Excitatory Transmission at Rat Hippocampal Synapses via Presynaptic Receptors.

S. Boehm and H. Betz (1997)
J. Neurosci. 17, 4066-4075
 |  Abstract »  |  Full Text »  |  PDF »

Somatostatin Receptors in the Diagnosis and Therapy of Neuroendocrine Tumors.

B. Wangberg, O. Nilsson, V. Johanson, L. Kolby, E. Forssell-Aronsson, P. Andersson, M. Fjalling, L.-E. Tisell, and H. Ahlman (1997)
Oncologist 2, 50-58
 |  Abstract »  |  Full Text »  |  PDF »

Depot Somatostatin Analogs--A New First Line Therapy for Acromegaly.

R. J. Robbins (1997)
J. Clin. Endocrinol. Metab. 82, 15-17
 |  Full Text »  |  PDF »

Modulation of High Voltage-Activated Calcium Channels by Somatostatin in Acutely Isolated Rat Amygdaloid Neurons.

F. Viana and B. Hille (1996)
J. Neurosci. 16, 6000-6011
 |  Abstract »  |  Full Text »  |  PDF »

Octreotide.

S. W.J. Lamberts, A.-J. van der Lely, W. W. de Herder, and L. J. Hofland (1996)
N. Engl. J. Med. 334, 246-254
 |  Full Text »  |  PDF »

Use of an Isotopic Somatostatin Receptor Probe to Image Gut Endocrine Tumors.

I. M. Modlin, E. Cornelius, and G. P. Lawton (1995)
Arch Surg 130, 367-374
 |  Abstract »  |  PDF »

Immunocytochemical Evidence for the Presence of Somatostatin-like Immunoreactive Nerves in Human Dental Pulp.

A. Casasco, A. Calligaro, M. Casasco, D.R. Springall, J.M. Polak, and C. Marchetti (1991)
Journal of Dental Research 70, 87-89
 |  Abstract »  |  PDF »

Treatment of an Enteric Fistula with Somatostatin in a Premature.

M.V. Julia, F.J. Parri, A. Albert, J. Figueras, J. Rovira, and L. Morales (1989)
Clinical Pediatrics 28, 149-150
 |  Abstract »  |  PDF »

Somatostatin and Somatostatin Analogue (SMS 201-995) in Treatment of Hormone-Secreting Tumors of the Pituitary and Gastrointestinal Tract and Non-Neoplastic Diseases of the Gut.

P. Gorden, R. J. Comi, P. N. Maton, and V. L. W. Go (1989)
Ann Intern Med 110, 35-50
 |  Abstract »  |  PDF »

A new prosomatostatin-derived peptide reveals a pattern for prohormone cleavage at monobasic sites.

R Benoit, N Ling, and F Esch (1987)
Science 238, 1126-1129
 |  Abstract »  |  PDF »

Somatostatin (Somatostatinlike) Immunoreactive Cells in the Human Inner Ear.

W. Arnold, H. J. Altermatt, R. Arnold, J.-O. Gebbers, and J. Laissue (1986)
Arch Otolaryngol Head Neck Surg 112, 934-937
 |  Abstract »  |  PDF »

Endocrine Mediators of Metabolism Associated with Injury and Sepsis.

M. S. Dahn, L. A. Jacobs, M. P. Lange, S. Smith, and R. A. Mitchell (1986)
JPEN J Parenter Enteral Nutr 10, 253-257
 |  Abstract »  |  PDF »

Patterns of growth hormone-releasing factor and somatostatin secretion into the hypophysial-portal circulation of the rat.

P. Plotsky and W Vale (1985)
Science 230, 461-463
 |  Abstract »  |  PDF »

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